Prevalence of sexual dimorphism in mammalian phenotypic traits

Role of sex as a modifier of a genotype–phenotype relationship: One of the first papers showing the role of sex in explaining variation in phenotypes of wildtype mice as assessed using data from the IMPC with all data freely available at mousephenotype.org. Furthermore, as a mediator of a mutant phenotype, sex modifies the genotype effect … Read more

Parenthood and the risk of cardiovascular diseases among 0.5 million men and women: Findings from the China Kadoorie Biobank

Women’s parity has been associated with risk of cardiovascular disease. It is unclear, however, whether it reflects biological effects of childbearing or uncontrolled socio-economic and lifestyle factors associated with childrearing. This study assessed the association between number of children and incident CVD outcomes, in women, but also in men. The study shows that the association … Read more