Sex differences in cerebral small vessel disease: A systematic review and meta-analysis

Resource type: Publication Publication
  • Authors
    Jimenez-Sanchez L.; Hamilton O.K.L.; Clancy U.; Backhouse E.V.; Stewart C.R.; Stringer M.S.; Doubal F.N.; Wardlaw J.M.
  • Type
    Original Research
  • Journal
    Frontiers in Neurology
  • Publication Date
    2021
  • Abstract

    Cerebral small vessel disease (SVD) is a common cause of stroke, mild cognitive impairment, dementia and physical impairments. Differences in SVD incidence or severity between males and females are unknown. We assessed sex differences in SVD by assessing the male-to-female ratio (M:F) of recruited participants and incidence of SVD, risk factor presence, distribution, and severity of SVD features.