Sex differences in D-dimer and critical illness in patients with COVID-19: A systematic review and meta-analysis

Resource type: Publication Publication
  • Authors
    Saville, Olivia; Elbatarny, Malak; Tera, Yousra; Deng, Yan; Othman, Maha
  • Type
    Original Research
  • Journal
    Research and Practice in Thrombosis and Haemostasis
  • Publication Date
    2023
  • Abstract

    Observed sex differences in COVID-19 outcomes suggest that men are more likely to experience critical illness and mortality. Thrombosis is common in severe COVID-19, and D-dimer is a significant marker for COVID-19 severity and mortality. It is unclear whether D-dimer levels differ between men and women, and the effect of D-dimer levels on disease outcomes remains under investigation. We aimed to evaluate the sex difference in the D-dimer level among hospitalized patients with COVID-19 and the effect of sex and D-dimer level on disease outcomes.

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