Age- and sex-related cortical gray matter volume differences in adolescent cannabis users: A systematic review and meta-analysis of voxel-based morphometry studies

Resource type: Publication Publication
  • Authors
    Allick A.; Park G.; Kim K.; Vintimilla M.; Rathod K.; Lebo R.; Nanavati J.; Hammond C.J.
  • Type
    Original research
  • Journal
    Frontiers in Psychiatry
  • Publication Date
    2021
  • Abstract

    Adolescent-onset cannabis use is rising in the era of marijuana legalization. Recent imaging studies have identified neuroanatomical differences between adult cannabis users and controls that are more prominent in early-onset users. Other studies point to sex-dependent effects of cannabis.

    A systematic review following PRISMA guidelines and subsequent effect-size seed-based d mapping (SDM) meta-analyses were conducted to investigate relationships between age (across the 12-to-21-year-old developmental window), sex, and gray matter volume (GMV) differences between cannabis using (CU) and typically developing (TD) youth.

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