Cardiometabolic and endocrine comorbidities in women with bipolar disorder: A systematic review

Resource type: Publication Publication
  • Authors
    Pahwa M.; Kucuker M.U.; Ho M.C.; Puspitasari A.; Moore K.M.; Betcher H.K.; Frye M.A.; Singh B.; Ozerdem A.; Veldic M.
  • Type
    Original research
  • Journal
    Journal of Affective Disorders
  • Publication Date
    2023
  • Abstract

    Bipolar Disorder (BD) is known to be equally distributed among males and females. The well-documented increased risk of medical comorbidities in patients with BD, in comparison to BD patients without medical comorbidities, shows a negative impact on the course of illness. There is some evidence suggesting that women with BD have higher psychiatric and medical comorbidities in comparison to men with BD, however there is no evidence in comparison to women without BD or other major psychiatric illness. These comorbidities, along with various psychosocial factors, are known to affect the course of BD.

    We aimed to systematically review the literature on cardiovascular, metabolic and endocrine comorbidities in women with BD in comparison to men with BD and control women. A comprehensive search of electronic databases including PubMed, PsycINFO, Embase, and SCOPUS was conducted, and a total of 61 identified studies were included in this review.

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