Contribution of sex and autoantibodies to microangiopathy assessed by nailfold videocapillaroscopy in systemic sclerosis: A systematic review of the literature

Resource type: Publication Publication
  • Authors
    van Leeuwen N.M.; Ciaffi J.; Schoones J.W.; Huizinga T.W.J.; de Vries-Bouwstra J.K.
  • Type
    Original research
  • Journal
    Arthritis Care and Research
  • Publication Date
    2021
  • Abstract
    Microangiopathy and dysregulation of the immune system play important roles in the pathogenesis of systemic sclerosis (SSc). Factors that trigger vascular injury in SSc have not been elucidated so far. We undertook this study to evaluate whether sex or expression of specific antinuclear autoantibodies might associate with the degree of microangiopathy through performance of a systematic review that summarizes what is known about these associations.