Gender-specific disparities in endovascular treatment of peripheral arterial occlusive disease: A systematic review of the literature

Background: There is evidence for gender disparities in the development, diagnostics and treatment of symptomatic peripheral arterial occlusive disease (PAOD). Although women represent 50% of treated cohorts in the literature, they only make up a small proportion in randomized trials on PAOD. Up to now, guidelines have included hardly any gender-sensitive recommendations and the results of observational studies are contradictory. This systematic literature review is aimed at identifying available observational studies on gender differences in the endovascular treatment of symptomatic PAOD.