Influence of sex-based differences on oral anticoagulation control in patients taking coumarin derivatives: A systematic review protocol

Resource type: Publication Publication
  • Authors
    Viana, Catiane Costa; Praxedes, Marcus Fernando da Silva; de Sousa, Waleska Jaclyn Freitas Nunes; Bartolazzi, Frederico; Vianna, Mayara Sousa; Silva, Jose Luiz Padilha da; Martins, Maria Auxiliadora Parreiras
  • Type
    Original research
  • Journal
    JBI Evidence Synthesis
  • Publication Date
    2021
  • Abstract

    Objective: This review will aim to assess the influence of sex-based differences on oral anticoagulation control in patients taking coumarin derivatives.

    Introduction: Coumarin derivatives, such as warfarin, have a narrow therapeutic index, requiring frequent monitoring to achieve adequate anticoagulation control, which can be assessed by the time in therapeutic range. Differences in the quality of oral anticoagulation control between men and women have been reported, although the current evidence is controversial. A systematic review on this topic would provide results that could be incorporated into clinical practice to enhance oral anticoagulation control and treatment outcomes.

Access Publication