Male-female differences in acute thoracic aortic dissection: A systematic review and meta-analysis

Resource type: Publication Publication
  • Authors
    Meccanici F.; Gokalp A.L.; Thijssen C.G.E.; Mokhles M.M.; Bekkers J.A.; Van Kimmenade R.; Verhagen H.J.; Roos-Hesselink J.W.; Takkenberg J.J.M.
  • Type
    Original research
  • Journal
    Interactive Cardiovascular and Thoracic Surgery
  • Publication Date
    2022
  • Abstract

    Objectives: This study aims to systematically review published literature on male-female differences in presentation, management and outcomes in patients diagnosed with acute thoracic aortic dissection (AD).

    Method(s): A systematic literature search was conducted for studies published between 1 January 1999 and 19 October 2020 investigating mortality and morbidity in adult patients diagnosed with AD. Patient and treatment characteristics were compared with odds ratios (ORs) and standardized mean differences and a meta-analysis using a random-effects model was performed for early mortality. Overall survival and reoperation were visualized by pooled Kaplan-Meier curves.

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