Prevalence of overweight and obesity in people with severe mental illness: Systematic review and meta-analysis

Resource type: Publication Publication
  • Authors
    Afzal M.; Siddiqi N.; Ahmad B.; Afsheen N.; Aslam F.; Ali A.; Ayesha R.; Bryant M.; Holt R.; Khalid H.; Ishaq K.; Koly K.N.; Rajan S.; Saba J.; Tirbhowan N.; Zavala G.A.
  • Type
    Original research
  • Journal
    Frontiers in Endocrinology
  • Publication Date
    2021
  • Abstract

    Aims: 1) To determine the pooled prevalence of overweight and obesity in people with severe mental illness (SMI), overall and by type of SMI, geographical region, and year of data collection; and 2) to assess the likelihood of overweight and obesity, in people with SMI compared with the general population.

    Method(s): PubMed, Medline, EMBASE, and PsycINFO databases were searched to identify observational studies assessing the prevalence of obesity in adults with SMI. Screening, data extraction and risk of bias assessments were performed independently by two co-authors. Random effect estimates for the pooled prevalence of overweight and obesity and the pooled odds of obesity in people with SMI compared with the general population were calculated. Subgroup analyses were conducted for types of SMI, setting, antipsychotic medication, region of the world, country income classification, date of data collection and sex. We assessed publication bias and performed a series of sensitivity analyses, excluding studies with high risk of bias, with low sample size and those not reporting obesity according to WHO classification.

Access Publication