Role of sex on the efficacy of pharmacological and non-pharmacological treatment of heart failure with reduced ejection fraction: A systematic review

Resource type: Publication Publication
  • Authors
    Sanroman Guerrero M.A.; Antonana Ugalde S.; Hernandez Sanchez E.; del Prado Diaz S.; Jimenez-Blanco Bravo M.; Cordero Pereda D.; Zamorano Gomez J.L.; Alvarez-Garcia J.
  • Type
    Original research
  • Journal
    Frontiers in Cardiovascular Medicine
  • Publication Date
    2022
  • Abstract

    Heart Failure (HF) is a growing epidemic with a similar prevalence in men and women. However, women have historically been underrepresented in clinical trials, leading to uneven evidence regarding the benefit of guideline-directed medical therapy (GDMT). This review aims to outline the sex differences in the efficacy of pharmacological and non-pharmacological treatment of HF with reduced ejection fraction (HFrEF).