Role of sex on the efficacy of pharmacological and non-pharmacological treatment of heart failure with reduced ejection fraction: A systematic review
Resource type:
Publication
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AuthorsSanroman Guerrero M.A.; Antonana Ugalde S.; Hernandez Sanchez E.; del Prado Diaz S.; Jimenez-Blanco Bravo M.; Cordero Pereda D.; Zamorano Gomez J.L.; Alvarez-Garcia J.
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TypeOriginal research
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JournalFrontiers in Cardiovascular Medicine
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Publication Date2022
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Abstract
Heart Failure (HF) is a growing epidemic with a similar prevalence in men and women. However, women have historically been underrepresented in clinical trials, leading to uneven evidence regarding the benefit of guideline-directed medical therapy (GDMT). This review aims to outline the sex differences in the efficacy of pharmacological and non-pharmacological treatment of HF with reduced ejection fraction (HFrEF).