Sex difference and outcome after percutaneous intervention in patients with chronic total occlusion: A systematic review and meta-analysis

Resource type: Publication Publication
  • Authors
    Mannem, Santhosh; Rattanawong, Pattara; Riangwiwat, Tanawan; Vutthikraivit, Wasawat; Putthapiban, Prapaipan; Sukhumthammarat, Weera; Kanitsoraphan, Chanavuth; Chongsathidkiet, Pakawat
  • Type
    Original research
  • Journal
    Cardiovascular Revascularization Medicine
  • Publication Date
    2020
  • Abstract

    Background: Recent studies suggest that sex difference is an outcome predictor in chronic total occlusion (CTO) patients who are undergoing percutaneous intervention (PCI). However, a systematic review and meta-analysis of the literature have not been done. We assessed the outcome of PCI in CTO between male and female.

    Methods: We comprehensively searched the databases of MEDLINE and EMBASE from inception to September 2017. Included studies were published cohort (prospective or retrospective) and case control studies of CTO patients who underwent PCI that compared successful procedure and major cardiac event (MACE), including cardiac death, target vessel revascularization, myocardial infarction, and stroke, between male and female. Data from each study were combined using the random-effects, generic inverse variance method of DerSimonian and Laird to calculate risk ratios and 95% confidence intervals.

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