Sex difference in clinical and procedural outcomes in patients undergoing coronary atherectomy: A systematic review and meta-analysis

Resource type: Publication Publication
  • Authors
    Thandra, Abhishek; Pajjuru, Venkat; Jhand, Aravdeep; Ponamgi, Shiva; Ismayl, Mahmoud; Torres, Rosa Cruz; Sharma, Arunima; Narmi, Ann; Agarwal, Himanshu; Kanmanthareddy, Arun
  • Type
    Original research
  • Journal
    Coronary Artery Disease
  • Publication Date
    2022
  • Abstract

    Background: Rotational and orbital coronary atherectomy (CA) are commonly utilized to treat complex calcified coronary lesions. We conducted a meta-analysis to evaluate sex differences in procedural complications and clinical outcomes after CA.

    Methods: PubMed, Google Scholar, and Cochrane databases were searched for all studies comparing sex differences in procedural and clinical outcomes following CA. The outcomes of interest were procedural complications (coronary dissection, stroke, major bleeding, coronary perforation, cardiac tamponade, and slow or no flow in target vessel) and the clinical outcomes (including early mortality, mid-term all-cause mortality, stroke, myocardial infarction, and target vessel revascularization). Pooled risk ratios (RRs) with their corresponding 95% confidence intervals (CIs) were calculated using the Mantel-Haenszel random-effects model.

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