Sex, race, and age differences of cardiovascular outcomes in cardiac resynchronization therapy RCTs: A systematic review and meta-analysis

Resource type: Publication Publication
  • Authors
    McKay B.; Tseng N.W.H.; Sheikh H.I.; Syed M.K.; Pakosh M.; Caterini J.E.; Sharma A.; Colella T.J.F.; Konieczny K.M.; Connelly K.A.; Graham M.M.; McDonald M.; Banks L.; Randhawa V.K.
  • Type
    Original Research
  • Journal
    CJC Open
  • Publication Date
    2021
  • Abstract

    Cardiac resynchronization therapy (CRT) is beneficial in patients who have heart failure with reduced ejection fraction or arrhythmic events. However, most randomized controlled trials (RCTs) showing survival benefits primarily enrolled older white men. This study aims to evaluate CRT efficacy by sex, race, and age in RCTs.