The prognostic importance of BCR-ABL transcripts in Chronic Myeloid Leukemia: A systematic review and meta-analysis.

Resource type: Publication Publication
  • Authors
    Ghalesardi, Omid Kiani; Khosravi, Abbas; Azizi, Ebrahim; Ahmadi, Seyed Esmaeil; Hajifathali, Abbas; Bonakchi, Hossein; Shahidi, Minoo
  • Type
    Original Research
  • Journal
    Leukemia Research
  • Publication Date
    2021
  • Abstract

    Chronic Myeloid Leukemia (CML) is characterized by the overproduction of BCR-ABL, a tyrosine kinase with constitutive activity, in which the majority of CML patients have e13a2 or e14a2 transcripts. Reckoned the possible associations between the hematologic and molecular features of the disease, a profound understanding of different aspects of this neoplasm would be provided.

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