Overall and sex-specific effect of berberine for the treatment of dyslipidemia in adults: A systematic review and meta-analysis of randomized placebo-controlled trials

Berberine is a nutraceutical that can improve lipid metabolism. Berberine may also affect sex hormones and exert sex-specific lipid-modifying effects, which have been overlooked. This study aimed to comprehensively review the efficacy and safety of berberine in adults for the treatment of dyslipidemia with consideration of potential sex disparity.